Table of Contents

Section 1: Understanding EBM
1.1: Pain - there's a lot of it about
1.2: Measuring pain
1.3: Outcomes
1.4: Clinical trial methods
1.5: Systematic review and meta-analysis
1.6: Size
1.7: Outputs and utility
1.8: Adverse events
1.9: Placebo
1.10: Being sure of a result
Section 2: Acute Pain
2.1: Introduction
2.2: League table of analgesics in acute pain
2.3: Aspirin in postoperative pain
2.4: Ibuprofen in postoperative pain
2.5: Paracetamol (acetaminophen) in acute postoperative pain
2.6: Paracetamol (acetaminophen) with codeine in acute postoperative pain
2.7: Diclofenac in postoperative pain
2.8: Injected morphine in postoperative pain
2.9: Dihydrocodeine in postoperative pain
2.10: Oral codeine in acute postoperative pain
2.11: Dextropropoxyphene alone and with paracetamol in postoperative pain
2.12: Intramuscular pethidine in postoperative pain
2.13: Naproxen in postoperative pain
2.14: Oral tramadol in postoperative pain
2.15: Paracetamol plus tramadol for acute pain
2.16: Oral rofexcoxib in postoperative pain
2.17: Transcutaneous electrical nerve stimulation (TENS) in acute postoperative pain and labour pain
2.18: Topically applied non-steroidal anti-inflammatory drugs in acute pain
2.19: Analgesics for dysmenorrhoea
2.20: Other acute pain interventions with evidence of efficacy
2.21: Other acute pain interventions without evidence of efficacy
2.22: Do NSAIDS inhibit bone healing?
Section 3: Migraine and Headache
3.1: Introduction
3.2: Diagnosing headache and migraine
3.3: Migraine: league tables of relative efficacy
3.4: Aspirin plus metoclopramide for acute migraine
3.5: Paracetamol for acute migraine
3.6: Ibuprofen for acute migraine
3.7: Sumatriptan for acute migraine
3.8: Oral naratriptan for acute migraine
3.9: Oral rizatriptan for acute migraine
3.10: Oral zolmitriptan for acute migraine
3.11: Oral eletriptan for acute migraine
3.12: Which migraine treatment strategy is most effective?
3.13: Prophylaxis for migraine
Section 4: Chronic Pain
4.1: Introduction
4.2: Antidepressants for diabetic neuropathy and postherpetic neuralgia
4.3: Anticonvulsants for diabetic neuropathy and postherpetic neuralgia
4.4: Topical capsaicin for pain relief
4.5: TENS for chronic pain
4.6: Fibromyalgia
4.7: Back Pain
4.8: Epidural corticosteroids for back pain
4.9: Steroid injections for shoulder and elbow disorders
4.10: Systemic local anaesthetic-type drugs in chronic pain
4.11: Cognitive behaviour therapy and behaviour therapy for chronic pain
4.12: Intravenous regional sympathetic blockade for reflex sympathetic dystrophy
4.13: Treatments for intermittent claudication
4.14: Cannabis for pain relief and for spasticity
Section 5: Arthritis
5.1: Arthritis and joints
5.2: Lifestyle and exercise
5.3: NSAIDs for treating Osteoarthritis
5.4: Topical applied NSAIDs for chronic pain
5.5: Coxibs for treating rheumatoid and osteoarthritis
5.6: Adverse effects of NSAIDs and coxibs
5.7: Paracetamol (acetaminophen) for osteoarthritis
5.8: TNF antibodies and rheumatoid arthritis
5.9: Fish Oil for rheumatoid arthritis
5.10: Sulfasalazine for rheumatoid arthritis
Section 6: Complementary and Alternative Therapies
6.1: Complementary and alternative therapies
6.2: Supplements and herbal remedies
6.3: Acupuncture
6.4: Homeopathy
6.5: Other complementary or alternative therapies for pain
Section 7: Cancer and Palliative Care
7.1: Cancer and palliative care
7.2: Non-steroidal anti-inflammatory drugs for cancer pain
7.3: Radiotherapy for painful bone metastases
7.4: Strontium 89 therapy for painful bony metastases
7.5: Intracerebroventricular opioid therapy compared with epidural and subarachnoid opioids for intractable cancer pain
7.6: Neurolytic coeliac plexus block (NCPB) for cancer pain
7.7: Nilutamide plus orchidectomy for metastatic prostatic cancer
7.8: Complementary therapy at the end of Life
7.9: Palliative care delivery system
Section 8: Management Issues
8.1: Easy targets are not always the right ones
8.2: Better prescribing of NSAIDs
8.3: Quality improvement by audit: Pain relief after day surgery
8.4: Improving oral postoperative analgesia
8.5: Do-it-yourself pain control
Section 9: Appendices
9.1: Glossary
9.2: Using the Oxman and Guyatt scoring system for reviews
9.3: Bandolier's 10 tips for healthy living
9.4: Cochrane Collaboration and Pain
9.5: Evidence based organisations, websites and resources

About the Author

Andrew Moore, Pain Research, Churchill Hospital, Oxford, UK, Jayne Edwards, Pain Research, Churchill Hospital, Oxford, U, Jodie Barden, Pain Research, Churchill Hospital, Oxford, U, Henry McQuay, Pain Research, Churchill Hospital, Oxford, U

Reviews

`This is an essential shelf/ visiting bag item for any GP. Well written and laid out (same size as the standard Oxford Handbooks so fits in your bag) I don't know what I'd do without it.'
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`Don't be put off by the title. Though concise and compact this is far from a 'little book' in every other respect. Moreover, its design arguably sets the standard... the brief text still delivers a punch... as truly pocket sized it has the advantage of being a mobile reference... this book is 5 star quality. This is an excellent reference. The authors arranged the book in such a way that it is easy for the reader to find a specific topic... This book will
be useful as a resource for all physicians.'
Doody's Journal