Table of Contents

Part 1: An overview of signalling
1: Aspects of cellular signalling
2: Pathways are the key to signalling
3: A look at some of the history and techniques of cell signalling
Part 2: Components that comprise signalling pathways
4: Extracellular signals: hormones, cytokines and growth factors
5: Detection of extracellular signals: the role of receptors
6: Protein phosphorylation, kinases and phosphatases
7: Cyclic nucleotides, cyclases and G proteins
8: Inositol phosphate metabolism and roles of membrane lipids
9: Intracellular calcium ions: control of their concentrations and roles in signalling
10: Reactive oxygen species, reactive nitrogen species and redox signalling
Part 3: Selected examples of signalling pathways and events
11: Insulin and the signal transduction cascades it invokes
12: Perception of the environment
13: Signalling in development and for the regulation of gene expression
14: Life, death and apoptosis
Part 4: Final thoughts
15: Cell signalling: importance, complexity and the future

About the Author

John Hancock is Professor of Cell Signalling at the University of the West of England. He has had a long standing interest in cell signalling and redox biology, and tries to bring these together as much as possible in his research. In addition to Cell Signalling he has published several reviews on nitric oxide and reactive oxygen species, and most recently on hydrogen sulfide.

Reviews

`A good overview of the key underlying concepts and principles, allowing students to gain a solid grounding in the subject. I like the Case Study sections which link to research findings; these provide relevant context and help students to understand the key message in complex scientific articles.'
Dr Andrew Chantry, University of East Anglia
`It is really the best specialist text for undergraduates on this topic I have seen.'
Dr Fergus Doherty, University of Nottingham
`Review from previous edition: John Hancock's Cell Signalling is a straightforward introduction to a rapidly expanding field of biology. Its unintimidating writing style, simple and uncluttered figures, and competitive price make it a wonderful introductory text for undergraduates.'
Dr Laura K. Palmer, Penn State University
`Review from previous edition: Complexity and specificity are the hallmarks of cell signalling, yet Hancock in this third edition has gone a long way to simplify these complicated processes. His signalling examples are clever and well-conceived, his writing descriptive and his passion for his subject infectious ... this is marvellous value for money and is a worthy companion to an undergraduate/postgraduate reference library.'
John P. Phelan, Waterford Institute of Technology, Ireland in The Biochemist