Table of Contents

GENERAL APPROACHES TO THE ANALYSIS OF COMPLEX SYNTHETIC PROBLEMS.

The Basis for Retrosynthetic Analysis.

Transform-Based Strategies.

Structure-Based and Topological Strategies.

Stereochemical Strategies.

Functional Group-Based and Other Strategies.

Concurrent Use of Several Strategies.

SPECIFIC PATHWAYS FOR THE SYNTHESIS OF COMPLEX MOLECULES.

Macrocyclic Structures.

Heterocyclic Structures.

Sesquiterpenoids.

Polycyclic Isoprenoids.

Prostanoids.

Leukotrienes and Other Bioactive Polyenes.

GUIDE TO THE ORIGINAL LITERATURE OF MULTISTEP SYNTHESIS.

Index.

About the Author

ELIAS JAMES COREY, winner of the 1990 Nobel Prize in Chemistry, is Sheldon Emery Professor in the Department of Chemistry at Harvard University. XUE-MIN CHENG is a Research Associate specializing in cardiovascular medicinal chemistry at Parke-Davis/Warner-Lambert Company.