Table of Contents

1. Building a Better Mouse: One Hundred Years of Genetics and Biology
2. Systematics of the genus Mus
3. The Secret World of Wild Mice
4. Breeding Systems: Considerations, Genetic Fundamentals, Genetic Background, and Strain Types
5. Mouse Strain and Genetic Nomenclature: an Abbreviated Guide
6. The Mouse Genome
7. Gene Mapping
8. Genetic Monitoring
9. Cytogenetics
10. Mouse Embryology: Research Techniques and a Comparison of Embryonic Development between Mouse and Man
11. Gamete and Embryo Manipulation
12. Chemical Mutagenesis in Mice
13. Gene-Specific Mutagenesis
14. Gene Transfer Studies Using Mouse Models
15. Mouse and Human Pluripotent Stem Cells
16. Drugs and the Mouse: Pharmacology, Pharmacogenetics, and Pharmacogenomics

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A primer to scientists new to the field of mouse research.

About the Author

Prof. Fox obtained his Master of Science degree in Medical Microbiology at Stanford University and a Doctor in Veterinary Medicine at Colorado State University, Fort Collins. Dr. Fox is an Adjunct Professor at Tufts University School of Veterinary Medicine and the University of Pennsylvania, School of Veterinary Medicine. He is a Diplomate and a past president of the American College of Laboratory Animal Medicine, past president of the Massachusetts Society of Medical Research, past chairman of AAALAC Council, and past chairman of the NCCR/NIH Comparative Medicine Study Section. He also is an elected fellow of the Infectious Disease Society of America. In 2004 Professor Fox was elected to the Institute of Medicine of the National Academy of Sciences.