1: Introduction
2: Metabolic innovation
3: Innovation through regulation
4: Novel molecules
5: The origins of evolutionary innovation
6: Genotype networks, self-organization, and natural selection
7: A synthesis of neutralism and selectionism
8: The role of robustness for innovation
9: Gene duplications and innovation
10: The role of recombination
11: Environmental change in adaptation and innovation
12: Evolutionary constraints and genotype spaces
13: Phenotypic plasticity and innovation
14: Towards continuous genotype spaces
15: Evolvable technology and innovation
16: Summary and outlook
Bibliography
Index
Andreas Wagner is professor in the Institute of Evolutionary
Biology and Environmental Science at the University of Zurich in
Switzerland, and External Professor at the Santa Fe Institute for
the study of Complex Systems. His main research interest is the
evolution of biological systems, from genes to complex biological
networks with thousands of components. He received his Ph.D in 1995
at Yale University, and has since held research fellowships at
several
institutions, such as the Institute for Advanced Studies in Berlin,
Germany, and the Institut des Hautes Etudes in Bures-sur-Yvette,
France. Author of more than 100 scientific publications and two
books, he
has lectured widely worldwide. He is a member of the Faculty of
1000 Biology, as well as of the editorial boards of several
scientific journals, including Bioessays, BMC Evolutionary biology,
Molecular Genetics and Genomics, and Molecular and Developmental
Evolution.
This book will surely be influential with the next generation of
evolutionary biologists, who will be able to digest and then apply
the significance of a network-centric view of adaptation. Such a
perspective will be essential for interpreting the increasing
number of empirical studies that recapitulate evolutionary
innovations in laboratory experiments. But even those molecular and
evolutionary biologists who do not actively work on problems of
innovation will benefit from the clarity of Wagner's theoretical
arguments, and the inspiring wealth of empirical examples that
demonstrate a new way to think of the dynamics of adaptation.
*Bioessays*
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