Table of Contents

Introduction
1: Bronwyn Kerr: How to evaluate a family history
2: Fred Menko: Guidelines for referral in Europe
3: Susan Domchek & Barbara L Weber: Guidelines for genetic counselling, testing and referral in North America
4: D Gareth Evans, Pål Moller & Bronwyn Kerr: Principles and applications of gene testing for common cancers
Risk assessment of common malignancies
5: D Gareth Evans, Bronwyn Kerr & Fiona Lalloo: Risk estimation in breast cancer
6: Fiona Lalloo: Risk estimation in colorectal cancer
7: D Gareth Evans: Risk estimation in ovarian cancer
8a: Pål Moller: Management of familial breast and ovarian cancer in Europe
8b: Barbara C McGillivray: Management of familial breast and ovarian cancer in North America
9: E Sheridan and R S Houlston: Management of familial adenomatous polyposis and other inherited polyposis syndromes
10: H F A Vasen, J Burn, E Sheridan, R S Houlston & F Douglas: Management of hereditary non-polyposis colorectal cancer
11: Sameer Jhavar & Rosalind Eeles: Management and risk assessment of less common familial cancers
Inherited cancer syndromes
12: J M Friedman: The neurofibromatoses
13: Eamonn R Maher: von Hippel-Lindau disease
14: Fiona Lalloo: Multiple endocrine neoplasias
15: D Gareth Evans: Gorlin Syndrome
16: J M Birch: The Li-Frameni Syndrome
17: Fiona Lalloo & D Gareth Evans: Other tumour predisposing syndromes
18: Patrick J Morrison: The ethical and insurance issues of cancer genetics

About the Author

Professor Evans is secretary of the UK Cancer Genetics Group. He was chairman of the UK National Institute of Clinical Excellence guidelines on familial breast cancer, Chairman of the International Collaborative Group on Familial Breast and Ovarian Cancer and on the Editorial Board of Familial Cancer.
Professor Friedman is Associate Editor of the journals Genetics in Medicine and Birth Defects Research: Clinical and Molecular Teratology, and a member of the editorial board of Clinical Genetics

Reviews

One of the commonest questions to a Clinical Genetics department is 'what do I do for this patient with a family history of cancer?' While most departments have guidelines for referral, these are intended to be for quick, easy-view reference. For those many clinicians who would like a little more detail, Lalloo and colleagues have produced this practical text with a worldwide list of contributors...it is easy to find the information you need in this book. Read it from cover to cover if it is valuable to your training or practice (or if you just like the subject) and you will have a comprehensive knowledge of what cancer genetics is about; keep it for reference, dipping into the particular bit you need from time to time, and your clinical genetics colleagues will be very impressed with your knowledge.
*Ulster Medical Journal*